10881018

Source:http://linkedlifedata.com/resource/pubmed/id/10881018

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026336, umls-concept:C0086418, umls-concept:C0153690, umls-concept:C0376358, umls-concept:C0449258
pubmed:issue	2
pubmed:dateCreated	2000-8-8
pubmed:abstractText	Clinically, the lethal phenotypes of human prostate cancer are characterized by their progression to androgen-independence and their propensity to form osseous metastases. We reported previously on the establishment of androgen-independent (AI) human prostate cancer cell lines derived from androgen-dependent (AD) LNCaP cells, with androgen independence defined as the capability of prostate cancer cells to grow in castrated hosts. One of the sublines, C4-2, was found to be AI, highly tumorigenic, and metastatic, having a proclivity for metastasis to the bone.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA63341, http://linkedlifedata.com/resource/pubmed/grant/CA63863
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8101368
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Dihydrotestosterone, http://linkedlifedata.com/resource/pubmed/chemical/Gentian Violet, http://linkedlifedata.com/resource/pubmed/chemical/Prostate-Specific Antigen, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	0270-4137
pubmed:author	pubmed-author:ChangS MSM, pubmed-author:ChungL WLW, pubmed-author:DegeorgesAA, pubmed-author:OzerAA, pubmed-author:PathakSS, pubmed-author:SikesR ARA, pubmed-author:ThalmannG NGN, pubmed-author:WuT TTT
pubmed:copyrightInfo	Copyright 2000 Wiley-Liss, Inc.
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	44
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	91-103 Jul 1;44(2)
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:10881018-Animals, pubmed-meshheading:10881018-Blotting, Northern, pubmed-meshheading:10881018-Bone Neoplasms, pubmed-meshheading:10881018-Cell Line, pubmed-meshheading:10881018-Dihydrotestosterone, pubmed-meshheading:10881018-Disease Models, Animal, pubmed-meshheading:10881018-Gene Expression Regulation, Neoplastic, pubmed-meshheading:10881018-Gentian Violet, pubmed-meshheading:10881018-Histocytochemistry, pubmed-meshheading:10881018-Humans, pubmed-meshheading:10881018-Image Processing, Computer-Assisted, pubmed-meshheading:10881018-Immunoenzyme Techniques, pubmed-meshheading:10881018-Karyotyping, pubmed-meshheading:10881018-Male, pubmed-meshheading:10881018-Mice, pubmed-meshheading:10881018-Mice, Inbred BALB C, pubmed-meshheading:10881018-Mice, Nude, pubmed-meshheading:10881018-Orchiectomy, pubmed-meshheading:10881018-Osteosarcoma, pubmed-meshheading:10881018-Prostate-Specific Antigen, pubmed-meshheading:10881018-Prostatic Neoplasms, pubmed-meshheading:10881018-RNA, Neoplasm, pubmed-meshheading:10881018-Specific Pathogen-Free Organisms, pubmed-meshheading:10881018-Tumor Cells, Cultured
pubmed:year	2000
pubmed:articleTitle	LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasis.
pubmed:affiliation	Department of Urology, University of Berne, Inselspital, Berne, Switzerland.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't