Linked Life Data

10880690

Source:http://linkedlifedata.com/resource/pubmed/id/10880690

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-8-28
pubmed:abstractText
Lactating rats (day 7 +/- 1 postpartum) were observed during a 1-h reunion with their pups 4 h after separation from them and 10 min after subcutaneous injection of saline (SAL; 0.1 ml) or low dosages of the dopamine agonist, apomorphine (APO; 0.1 or 0.25 mg/kg). Although APO did not affect latency to sniff pups or retrieve the first pup, there were dosage-dependent delays in onset of licking and nursing pups, and decreases in retrieval and grouping of pups, nursing duration, and litter weight gain. The alterations in maternal responsiveness among APO-treated dams were related to increased carrying and mouthing of pups and markedly increased sniffing of pups, bedding, and cage. Duration of time spent licking pups, exploring, and self-grooming did not differ between groups. Thus, certain APO-induced stereotypic behaviors interfered with the normal sequence of maternal behavior by exaggerating some components and delaying others. These results are relevant to disturbances in maternal behavior caused by hyperreactivity or by other drugs that increase dopaminergic activity, such as cocaine.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Effects of low dosages of apomorphine on maternal responsiveness in lactating rats.
pubmed:affiliation
Department of Psychology, Rutgers-The State University of New Jersey, New Brunswick, NJ 08903, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't