Linked Life Data

10879708

Source:http://linkedlifedata.com/resource/pubmed/id/10879708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-10-12
pubmed:abstractText
Clinical studies report a rate of 5% and autopsy results a rate of 25% of brain involvement in sarcoidosis. The aim of this study was to evaluate the role of radiology in the diagnosis of patients with neurosarcoidosis. The chest radiographs and MRI brain scans of 22 patients with sarcoidosis were retrospectively reviewed, along with the information that was provided in the request form and clinical charts. All patients had neurological signs and symptoms; 21 patients were examined with contrast enhancement. Facial nerve paralysis was the most common clinical manifestation identified in 10 patients. A wide spectrum of MR findings was noted: periventricular high-signal lesions on T2-weighted images (46%); multiple supratentorial and infratentorial brain lesions (36%); solitary intra-axial mass (9%); solitary extra-axial mass (5%); and leptomeningeal enhancement (36%). Neurological signs and symptoms can be significant manifestations of sarcoidosis. Magnetic resonance imaging shows a wide spectrum of brain abnormalities associated with neurosarcoidosis. The patient's history and chest X-ray are helpful in arriving at the correct diagnosis, but in selected cases with isolated brain involvement biopsy may still be required.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0938-7994
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
941-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Role of radiology in the diagnosis of neurosarcoidosis.
pubmed:affiliation
Department of Diagnostic Radiology, Faculty of Medicine, Martin Luther University, Halle/Saale, Germany.
pubmed:publicationType
Journal Article