Linked Life Data

10876852

Source:http://linkedlifedata.com/resource/pubmed/id/10876852

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pubmed-article:10876852pubmed:abstractTextThe influence of whole-cell and acellular pertussis vaccines, introduced both alone and in combination with N-acetylglucosaminylmuramyl-2-alanine-D-isoglutamine (GMDP) on the activity of two enzymes of peritoneal exudate macrophages (5'-nucleotidase and Na+K(+)-adenosine triphosphatase) was studied. The study revealed that both pertussis vaccines exhibited immunomodulating properties, these properties being most pronounced in whole-cell pertussis vaccine. The use of GMDP in combination with pertussis vaccines led to changes in the enzymatic activity of peritoneal exudate macrophages, which was indicative of a decrease in the immunomodulating action of pertussis preparations.lld:pubmed
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pubmed-article:10876852pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10876852pubmed:articleTitle[The action of pertussis vaccines and GMDP on the change in the enzymatic activity of macrophages from peritoneal exudate].lld:pubmed
pubmed-article:10876852pubmed:affiliationMechnikov Research Institute for Vaccines and Sera, Moscow, Russia.lld:pubmed
pubmed-article:10876852pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10876852pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:10876852pubmed:publicationTypeEnglish Abstractlld:pubmed