Source:http://linkedlifedata.com/resource/pubmed/id/10866377
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2000-11-7
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pubmed:abstractText |
Two analogues of bovine beta-casomorphin-7 and beta-casomorphin-5 containing a beta-homo phenylalanine in substitution of the phenylalanine in position 3 were synthesised and tested for their mu-opioid receptor affinity. The modification enhanced the mu receptor affinity 5-fold in the case of modified beta-CM-7 and 2-fold for modified beta-CM-5 when compared to the natural peptides.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1185-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10866377-Amino Acid Sequence,
pubmed-meshheading:10866377-Animals,
pubmed-meshheading:10866377-Cattle,
pubmed-meshheading:10866377-Endorphins,
pubmed-meshheading:10866377-Phenylalanine,
pubmed-meshheading:10866377-Protein Binding,
pubmed-meshheading:10866377-Rats,
pubmed-meshheading:10866377-Receptors, Opioid, mu
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pubmed:year |
2000
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pubmed:articleTitle |
Beta-casomorphins: substitution of phenylalanine with beta-homo phenylalanine increases the mu-type opioid receptor affinity.
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pubmed:affiliation |
Dipartinento di Scienza degli Alimenti, Università di Napoli Federico II, Portici, Italy. luilongo@unina.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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