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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2000-6-29
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pubmed:abstractText |
The cardiac LIM domain protein MLP, a member of the cysteine-rich protein family, is an essential regulator of cardiac muscle development. Mice with a disruption of the MLP gene resemble the morphological and clinical picture of dilated cardiomyopathy and heart failure in humans. We investigated whether altered MLP expression is significant for the pathogenesis of human heart failure.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
13
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2674-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10851202-Adult,
pubmed-meshheading:10851202-Cardiomyopathy, Dilated,
pubmed-meshheading:10851202-Chronic Disease,
pubmed-meshheading:10851202-Down-Regulation,
pubmed-meshheading:10851202-Gene Expression,
pubmed-meshheading:10851202-Heart Failure,
pubmed-meshheading:10851202-Humans,
pubmed-meshheading:10851202-LIM Domain Proteins,
pubmed-meshheading:10851202-Middle Aged,
pubmed-meshheading:10851202-Muscle Proteins,
pubmed-meshheading:10851202-Myocardial Ischemia,
pubmed-meshheading:10851202-Myocardium,
pubmed-meshheading:10851202-Myofibrils,
pubmed-meshheading:10851202-Protein Binding,
pubmed-meshheading:10851202-Protein Structure, Tertiary,
pubmed-meshheading:10851202-RNA, Messenger,
pubmed-meshheading:10851202-Subcellular Fractions,
pubmed-meshheading:10851202-Zinc Fingers
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pubmed:year |
2000
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pubmed:articleTitle |
Decreased expression of the cardiac LIM domain protein MLP in chronic human heart failure.
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pubmed:affiliation |
Klinik III für Innere Medizin, Universität zu Köln, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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