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rdf:type |
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lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0007818,
umls-concept:C0025519,
umls-concept:C0032743,
umls-concept:C0034693,
umls-concept:C0038525,
umls-concept:C0063146,
umls-concept:C0355642,
umls-concept:C0373440,
umls-concept:C0428714,
umls-concept:C0445202,
umls-concept:C0677582,
umls-concept:C0871261,
umls-concept:C1003377,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2603343,
umls-concept:C2911692
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pubmed:issue |
6
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pubmed:dateCreated |
2000-6-14
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pubmed:abstractText |
The hydroxyl radical scavenger (+/-)-N,N'-propylenedinicotinamide (AVS) has been shown to ameliorate the occurrence of vasospasm following experimental subarachnoid hemorrhage (SAH) and to reduce the incidence of delayed ischemic neurological deficits (DINDs) in patients with SAH. The authors investigated whether prophylactic administration of AVS could improve cerebral blood flow (CBF) and cerebral glucose utilization (CGU) following SAH in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1009-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10839263-Animals,
pubmed-meshheading:10839263-Brain,
pubmed-meshheading:10839263-Cerebrovascular Circulation,
pubmed-meshheading:10839263-Free Radical Scavengers,
pubmed-meshheading:10839263-Glucose,
pubmed-meshheading:10839263-Male,
pubmed-meshheading:10839263-Niacinamide,
pubmed-meshheading:10839263-Postoperative Period,
pubmed-meshheading:10839263-Rats,
pubmed-meshheading:10839263-Rats, Sprague-Dawley,
pubmed-meshheading:10839263-Subarachnoid Hemorrhage,
pubmed-meshheading:10839263-Tomography, Emission-Computed,
pubmed-meshheading:10839263-Vasospasm, Intracranial
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pubmed:year |
2000
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pubmed:articleTitle |
Improvement in cerebral blood flow and metabolism following subarachnoid hemorrhage in response to prophylactic administration of the hydroxyl radical scavenger, AVS, (+/-)-N,N'-propylenedinicotinamide: a positron emission tomography study in rats.
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pubmed:affiliation |
Department of Neurosurgery, Hamamatsu University School of Medicine, Japan. seijiy@hama-med.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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