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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Pt 1
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pubmed:dateCreated |
1979-7-16
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pubmed:abstractText |
Motilin-immunoreactive cells in the human and monkey duodenum and upper jejunum were investigated by immunofluorescence (IF) and peroxidase-antiperoxidase (PAP) techniques using antibodies against synthetic 13-norleucine motilin and synthetic porcine motilin. Contrary to previous reports, we have demonstrated that motilin-immunoreactive cells are a distinct cell population that does not correspond to 5-hydroxytryptamine-containing enterochromaffin (EC-) cells. EC-cells, indentified by formaldehyde-induced fluorescence (FIF) or by argentaffinity (AA), do not react with either antisera. EC-cells of the monkey, utilizing one method (PAP), reacted to one antiserum very weakly. This reaction was also suppressed by absorption with 13-norleucine motilin. It is suggested that the EC-cells of the monkey contain either a very small amount of motilin or another peptide that exhibits a part of the amino acid sequence of motilin. The discrepancy between these results and those of other authors can be explained by the different reactivity of the antisera used.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0016-5085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
897-902
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:108174-Animals,
pubmed-meshheading:108174-Chromaffin System,
pubmed-meshheading:108174-Duodenum,
pubmed-meshheading:108174-Enterochromaffin Cells,
pubmed-meshheading:108174-Fluorescent Antibody Technique,
pubmed-meshheading:108174-Gastrointestinal Hormones,
pubmed-meshheading:108174-Haplorhini,
pubmed-meshheading:108174-Humans,
pubmed-meshheading:108174-Ileum,
pubmed-meshheading:108174-Immunoenzyme Techniques,
pubmed-meshheading:108174-Intestine, Small,
pubmed-meshheading:108174-Jejunum,
pubmed-meshheading:108174-Motilin,
pubmed-meshheading:108174-Serotonin
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pubmed:year |
1979
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pubmed:articleTitle |
Immunohistochemical localization of motilin in endocrine non-enterochromaffin cells of the small intestine of humans and monkey.
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pubmed:publicationType |
Journal Article
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