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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
02
|
| pubmed:dateCreated |
1975-11-7
|
| pubmed:abstractText |
In normal and lymphostatic encephalopathic rats, aprotinin pretreatment alters the duration of the harmine tremor and the cerebral concentration of the alkaloid; low doses shorten the tremor and decrease the concentration, a high dose causes the opposite. Aprotinin may decrease or increase the blood-brain barrier permeability of harmine. Because the findings are similar in both groups of rats the blood-brain barrier for harmine is assumed to be intact in lymphostatic encephalopathy. However, sick rats possibly suffer from an impaired cerebral elimination of harmine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0014-2999
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
32
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
364-9
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1080114-Alkaloids,
pubmed-meshheading:1080114-Animals,
pubmed-meshheading:1080114-Aprotinin,
pubmed-meshheading:1080114-Blood Proteins,
pubmed-meshheading:1080114-Brain Chemistry,
pubmed-meshheading:1080114-Brain Diseases,
pubmed-meshheading:1080114-Harmine,
pubmed-meshheading:1080114-Lymph Nodes,
pubmed-meshheading:1080114-Male,
pubmed-meshheading:1080114-Protein Binding,
pubmed-meshheading:1080114-Rats,
pubmed-meshheading:1080114-Time Factors,
pubmed-meshheading:1080114-Tremor
|
| pubmed:articleTitle |
The effect of aprotinin on the harmine-induced tremor in lymphostatic encephalopathic and normal rats.
|
| pubmed:publicationType |
Journal Article
|