rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2000-5-25
|
pubmed:abstractText |
Our previous studies confirmed that tacrolimus (FK506) and sirolimus [rapamycin (RAPA)], in combination, are not antagonistic but are synergistic in the prolongation of heart and small bowel grafts in the rodent. The aim of this study was to confirm further the synergistic effect of combined FK506 and RAPA in the more clinically relevant model, kidney transplantation in monkeys.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0041-1337
|
pubmed:author |
pubmed-author:BekerskyII,
pubmed-author:ChenHH,
pubmed-author:DalozePP,
pubmed-author:FitzsimmonsW EWE,
pubmed-author:LángJJ,
pubmed-author:PeetzSS,
pubmed-author:PyBB,
pubmed-author:SehgalSS,
pubmed-author:WUM CMC,
pubmed-author:WuJJ,
pubmed-author:XuDD
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
69
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1275-83
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10798741-Animals,
pubmed-meshheading:10798741-Body Weight,
pubmed-meshheading:10798741-Cercopithecus aethiops,
pubmed-meshheading:10798741-Drug Synergism,
pubmed-meshheading:10798741-Drug Therapy, Combination,
pubmed-meshheading:10798741-Glucose Tolerance Test,
pubmed-meshheading:10798741-Graft Rejection,
pubmed-meshheading:10798741-Graft Survival,
pubmed-meshheading:10798741-Immunosuppressive Agents,
pubmed-meshheading:10798741-Kidney,
pubmed-meshheading:10798741-Kidney Transplantation,
pubmed-meshheading:10798741-Male,
pubmed-meshheading:10798741-Sirolimus,
pubmed-meshheading:10798741-Tacrolimus,
pubmed-meshheading:10798741-Time Factors
|
pubmed:year |
2000
|
pubmed:articleTitle |
Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey.
|
pubmed:affiliation |
Laboratories of Experimental Surgery and Transplantation Immunology, University of Montreal, Notre-Dame Hospital, Quebec, Canada.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|