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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-5-25
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pubmed:abstractText |
Hyper-IL-6, a fusion protein of interleukin-6 and its specific receptor, together with stem cell factor leads to the proliferation of primitive hematopoietic progenitor cells. Based on these findings, the current study examined whether hyper-IL-6 promotes the growth of precursor cells that can be further differentiated into dendritic cells in the presence of additional cytokines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokine Receptor gp130,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Granulocyte-Macrophage...,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Core Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/IL6ST protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Oxytocics,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Stem Cell Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/interleukin 6-interleukin 6...
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0301-472X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
365-72
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10781894-Antigen Presentation,
pubmed-meshheading:10781894-Antigens, CD,
pubmed-meshheading:10781894-CD4-Positive T-Lymphocytes,
pubmed-meshheading:10781894-Cell Differentiation,
pubmed-meshheading:10781894-Cell Division,
pubmed-meshheading:10781894-Cells, Cultured,
pubmed-meshheading:10781894-Cytokine Receptor gp130,
pubmed-meshheading:10781894-Dendritic Cells,
pubmed-meshheading:10781894-Dinoprostone,
pubmed-meshheading:10781894-Flow Cytometry,
pubmed-meshheading:10781894-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:10781894-Hematopoietic Stem Cells,
pubmed-meshheading:10781894-Hepatitis B Core Antigens,
pubmed-meshheading:10781894-Humans,
pubmed-meshheading:10781894-Immunophenotyping,
pubmed-meshheading:10781894-Interleukin-1,
pubmed-meshheading:10781894-Interleukin-4,
pubmed-meshheading:10781894-Interleukin-6,
pubmed-meshheading:10781894-Membrane Glycoproteins,
pubmed-meshheading:10781894-Oxytocics,
pubmed-meshheading:10781894-Receptors, Interleukin,
pubmed-meshheading:10781894-Receptors, Interleukin-6,
pubmed-meshheading:10781894-Recombinant Fusion Proteins,
pubmed-meshheading:10781894-Recombinant Proteins,
pubmed-meshheading:10781894-Stem Cell Factor,
pubmed-meshheading:10781894-Tumor Necrosis Factor-alpha
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pubmed:year |
2000
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pubmed:articleTitle |
The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells.
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pubmed:affiliation |
III Medizinische Klinik, Technische Universität München, München, Germany. helga.bernhard@lrz.tu-muenchen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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