Linked Life Data

10768144

Source:http://linkedlifedata.com/resource/pubmed/id/10768144

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-5-17
pubmed:abstractText
This paper discusses the concept of epilepsy intractability as the criterium qualifying for the administration of polytherapy, inclusion of new antiepileptic drugs /AEDs/ and application of neurosurgical treatment. There were also diagnostic criteria and complication discussed. To define the concept of epilepsy intractability correctly and to administer appropriate treatment, it is necessary to classify the kind of seizures and their possible reasons, to apply suitable AEDs, their doses and to treat patients with them for a suitable period of time. Intractable forms of epilepsy are diagnosed at about 20-30% of patients with suitable treatment. The disease prevalence is different at particular age groups and depends also on seizure type or epileptic syndrome. Therefore, Ohtahar syndrome, West, Lennox and Gastaut syndromes, epilepsia partialis continua belong to intractable epileptic syndromes at children. There is the biggest risk of psychic disorders appearance among patients resistant to antiepileptic treatment. Moreover, long-term application of AEDs may be associated with the induction of epileptic seizures, occurrence of side and toxic symptoms. Great interest in intractable epilepsy is connected with huge progress in treatment of this disease which has resulted in introduction of many new AEDs for the last few years. Its inclusion into treatment, first as add--on therapy, and then, due to clinical examinations, also as a monotherapy, enables the improvement in seizure control and in the quality of patients' life.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-3843
pubmed:author
pubmed:issnType
Print
pubmed:volume
34 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
37-48
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Intractable epilepsy of childhood and its treatment].
pubmed:affiliation
Katedra i Klinika Neurologii Wieku Rozwojowego AM.
pubmed:publicationType
Journal Article, English Abstract, Review