Source:http://linkedlifedata.com/resource/pubmed/id/10746779
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2000-6-21
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pubmed:abstractText |
As a basis for studing the essential cellular processes of hyperthermophilic archaea, thermosensitive mutants of Sulfolobus acidocaldarius were isolated and characterized. Exponential-phase liquid cultures were shifted to the nonpermissive temperature and growth, viability, and distributions of cell mass and DNA content were measured as a function of time after the shift. The observed phenotypes demonstrate that chromosome replication, nucleoid organization, nucleoid partition and cell division, which normally are tightly co-ordinated during cellular growth, can be inhibited or uncoupled by mutation in this hyperthermophilic archaeon.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1350-0872
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
146 ( Pt 3)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
749-57
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10746779-Cell Cycle,
pubmed-meshheading:10746779-Culture Media,
pubmed-meshheading:10746779-DNA, Archaeal,
pubmed-meshheading:10746779-Flow Cytometry,
pubmed-meshheading:10746779-Mutation,
pubmed-meshheading:10746779-Phenotype,
pubmed-meshheading:10746779-Sulfolobus acidocaldarius,
pubmed-meshheading:10746779-Temperature
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pubmed:year |
2000
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pubmed:articleTitle |
Altered patterns of cellular growth, morphology, replication and division in conditional-lethal mutants of the thermophilic archaeon Sulfolobus acidocaldarius.
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pubmed:affiliation |
Department of Cell and Molecular Biology, Biomedical Center, Uppsala University, Sweden. Rolf.Bernander@icm.uu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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