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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-5-11
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pubmed:abstractText |
Anti-platelet drug therapy is currently performed without monitoring, because the established method of platelet aggregometry is cumbersome. The recently developed platelet function analyzer PFA-100 measures shear stress dependent, collagen epinephrine (CEPI) and collagen adenosine diphosphate (CADP) induced platelet plug formation. As the PFA-100 provides a valuable tool to detect patients with platelet dysfunction more efficiently and cost-effectively than aggregometry, we investigated its potential to monitor the efficacy of aspirin treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Diphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Aspirin,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Epinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrinolytic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Integrin alpha2,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Thromboxane B2,
http://linkedlifedata.com/resource/pubmed/chemical/von Willebrand Factor
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0340-6245
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
316-21
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10739392-Adenosine Diphosphate,
pubmed-meshheading:10739392-Adult,
pubmed-meshheading:10739392-Antigens,
pubmed-meshheading:10739392-Antigens, CD,
pubmed-meshheading:10739392-Aspirin,
pubmed-meshheading:10739392-Blood Coagulation Tests,
pubmed-meshheading:10739392-Blood Platelets,
pubmed-meshheading:10739392-Collagen,
pubmed-meshheading:10739392-Cross-Over Studies,
pubmed-meshheading:10739392-Dose-Response Relationship, Drug,
pubmed-meshheading:10739392-Double-Blind Method,
pubmed-meshheading:10739392-Epinephrine,
pubmed-meshheading:10739392-Female,
pubmed-meshheading:10739392-Fibrinolytic Agents,
pubmed-meshheading:10739392-Flow Cytometry,
pubmed-meshheading:10739392-Genotype,
pubmed-meshheading:10739392-Homozygote,
pubmed-meshheading:10739392-Humans,
pubmed-meshheading:10739392-Integrin alpha2,
pubmed-meshheading:10739392-Longitudinal Studies,
pubmed-meshheading:10739392-Male,
pubmed-meshheading:10739392-Platelet Aggregation,
pubmed-meshheading:10739392-Platelet Aggregation Inhibitors,
pubmed-meshheading:10739392-Platelet Count,
pubmed-meshheading:10739392-Point Mutation,
pubmed-meshheading:10739392-Prospective Studies,
pubmed-meshheading:10739392-Thromboxane B2,
pubmed-meshheading:10739392-Time Factors,
pubmed-meshheading:10739392-von Willebrand Factor
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pubmed:year |
2000
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pubmed:articleTitle |
Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100.
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pubmed:affiliation |
Department of Clinical Pharmacology-TARGET, Vienna University Hospital School of Medicine, Austria.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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