Source:http://linkedlifedata.com/resource/pubmed/id/10735625
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-4-12
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pubmed:abstractText |
Post-transplant lymphoproliferative disorders (PT-LPD) are a well-known complication of organ transplantation. Their incidence after liver transplantation in adults ranges from 1.8 to 4%. Reduction of immunosuppression led to remission in a few cases. Other treatments include chemotherapy, interferon alpha therapy and/or intravenous-immunoglobulins, or antiviral drugs. However, monoclonal antibodies directed against B-cell specific antigens have rarely been used in those patients. Our aim was to study the feasibility and efficacy of Rituximab, a new, promising human chimeric antibody that recognizes the CD20 antigen, for the treatment of patients with clonal lymphoproliferative disorders after orthotopic liver transplantation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
521-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10735625-Adult,
pubmed-meshheading:10735625-Aged,
pubmed-meshheading:10735625-Antibodies, Monoclonal,
pubmed-meshheading:10735625-Antibodies, Monoclonal, Murine-Derived,
pubmed-meshheading:10735625-Biopsy,
pubmed-meshheading:10735625-Female,
pubmed-meshheading:10735625-Humans,
pubmed-meshheading:10735625-Liver,
pubmed-meshheading:10735625-Liver Transplantation,
pubmed-meshheading:10735625-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:10735625-Lymphoma, Non-Hodgkin,
pubmed-meshheading:10735625-Lymphoproliferative Disorders,
pubmed-meshheading:10735625-Male,
pubmed-meshheading:10735625-Postoperative Complications,
pubmed-meshheading:10735625-Remission Induction,
pubmed-meshheading:10735625-Treatment Failure
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pubmed:year |
2000
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pubmed:articleTitle |
Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with clonal lymphoproliferative disorders after orthotopic liver transplantation: a report of three cases.
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pubmed:affiliation |
Service d'Hématologie, Hôpital Cochin, Paris, France.
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pubmed:publicationType |
Journal Article,
Case Reports
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