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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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|
pubmed:dateCreated |
2000-4-11
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|
pubmed:abstractText |
Severity of pancreatitis seems to be aggravated by impairment of vascular perfusion of the gland. Early mortality occurs within the first few days from the acute consequences of pancreatic injury with subsequent inflammatory response. Because vasoactive substances, including endothelin, seem to contribute to early mortality in acute pancreatitis, we tested the hypothesis that the inhibition of endothelin action could alter the outcome after severe experimental pancreatitis.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0169-4197
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
26
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
147-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10732291-Animals,
pubmed-meshheading:10732291-Bile Acids and Salts,
pubmed-meshheading:10732291-Endothelins,
pubmed-meshheading:10732291-Female,
pubmed-meshheading:10732291-Pancreatitis, Acute Necrotizing,
pubmed-meshheading:10732291-Random Allocation,
pubmed-meshheading:10732291-Rats,
pubmed-meshheading:10732291-Rats, Wistar,
pubmed-meshheading:10732291-Sulfonamides,
pubmed-meshheading:10732291-Taurocholic Acid,
pubmed-meshheading:10732291-Treatment Failure
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|
pubmed:year |
1999
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|
pubmed:articleTitle |
The endothelin antagonist bosentan does not improve survival in severe experimental pancreatitis in rats.
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|
pubmed:affiliation |
Institut für Anästhesie, Universität Heidelberg, Mannheim, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
