Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-4-4
pubmed:abstractText
Spotting lethal (sl) rats, a model for Hirschsprung's disease, recently have been found to carry a deletion in the endothelin B (ET(B)) gene, causing functional lack of ET(B) receptors. The ET(B) receptor mediates, together with and in counterbalance to the ET(A) receptor, endothelin actions on vessels, cell proliferation, and migration. The authors investigated the effect of homozygosity (sI/sI) or heterozygosity (+/sl) on phenotype, intestinal morphology, and survival.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3468
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
480-8
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:10726693-Animals, pubmed-meshheading:10726693-Colon, pubmed-meshheading:10726693-Disease Models, Animal, pubmed-meshheading:10726693-Enzyme Induction, pubmed-meshheading:10726693-Heterozygote, pubmed-meshheading:10726693-Hirschsprung Disease, pubmed-meshheading:10726693-Homozygote, pubmed-meshheading:10726693-Immunohistochemistry, pubmed-meshheading:10726693-Liver, pubmed-meshheading:10726693-Nitric Oxide Synthase, pubmed-meshheading:10726693-Nutrition Disorders, pubmed-meshheading:10726693-Phenotype, pubmed-meshheading:10726693-Rats, pubmed-meshheading:10726693-Rats, Mutant Strains, pubmed-meshheading:10726693-Rats, Wistar, pubmed-meshheading:10726693-Receptors, Endothelin, pubmed-meshheading:10726693-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:10726693-Sepsis, pubmed-meshheading:10726693-Serum Albumin, pubmed-meshheading:10726693-Spleen
pubmed:year
2000
pubmed:articleTitle
Phenotype, intestinal morphology, and survival of homozygous and heterozygous endothelin B receptor--deficient (spotting lethal) rats.
pubmed:affiliation
Max-Planck-Institute for Experimental Medicine and Department of Neurology, Georg-August-University, Göttingen, Germany.
pubmed:publicationType
Journal Article