Source:http://linkedlifedata.com/resource/pubmed/id/10706912
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2000-4-12
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pubmed:abstractText |
This collective review includes all available case reports of smooth muscle (stromal) tumors of the esophagus in the world literature. Compiling this review, we endeavored to examine cumulative and recently collected data of both benign and malignant esophageal smooth muscle tumors found in the literature spanning the period from 1875 to 1996, which totaled 1679 leiomyomas (LMs) and 165 leiomyosarcomas (LMSs). The peak age of occurrence of benign smooth muscle tumors in the esophagus was found to be between the ages of 30 and 59, whereas the highest frequency of malignant tumors was seen later in life, during the decade from age 60 to 69. The most common location of both LMs and LMSs was the lower third of the esophagus. Their patterns of growth differed; LMs were more likely to grow intramurally, and LMSs were predominantly intraluminal. Most patients with LMs presented with dysphagia and pain or discomfort; patients with LMSs additionally commonly complained of weight loss. As with smooth muscle tumors of other areas of the gastrointestinal tract, the duration of symptoms averaged 1 month to 1 year, and malignant tumors grew to larger sizes than benign neoplasms. Approximately one-third of LMSs had metastasized at diagnosis, and there was a 5-year survival rate of approximately 20%.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0364-2313
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
401-11
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:10706912-Adult,
pubmed-meshheading:10706912-Age Factors,
pubmed-meshheading:10706912-Aged,
pubmed-meshheading:10706912-Deglutition Disorders,
pubmed-meshheading:10706912-Esophageal Neoplasms,
pubmed-meshheading:10706912-Female,
pubmed-meshheading:10706912-Humans,
pubmed-meshheading:10706912-Leiomyoma,
pubmed-meshheading:10706912-Leiomyosarcoma,
pubmed-meshheading:10706912-Male,
pubmed-meshheading:10706912-Middle Aged,
pubmed-meshheading:10706912-Survival Rate,
pubmed-meshheading:10706912-Time Factors,
pubmed-meshheading:10706912-Weight Loss
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pubmed:year |
2000
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pubmed:articleTitle |
Tumors of the esophagus.
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pubmed:affiliation |
Centers for Surgical Anatomy and Technique, Emory University School of Medicine, 1462 Clifton Road, NE, Suite 303, Atlanta, Georgia 30322, USA.
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pubmed:publicationType |
Journal Article,
Review
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