|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2000-4-4
|
|
pubmed:abstractText |
Upregulated matrix synthesis is a hallmark of systemic sclerosis (SSc). There are indications that growth factors such as platelet derived growth factor (PDGF) are involved in proliferative pathways in SSc lesions. As activated complement releases PDGF from endothelial cells, we searched for activated complement and the complement receptor for C5a (C5aR) in skin biopsies of patients with SSc.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0315-162X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
27
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
402-4
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10685805-Antigens, CD,
pubmed-meshheading:10685805-Biopsy,
pubmed-meshheading:10685805-Complement C5a,
pubmed-meshheading:10685805-Complement Membrane Attack Complex,
pubmed-meshheading:10685805-Humans,
pubmed-meshheading:10685805-Receptor, Anaphylatoxin C5a,
pubmed-meshheading:10685805-Receptors, Complement,
pubmed-meshheading:10685805-Scleroderma, Systemic,
pubmed-meshheading:10685805-Skin
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Detection of activated complement complex C5b-9 and complement receptor C5a in skin biopsies of patients with systemic sclerosis (scleroderma).
|
|
pubmed:affiliation |
WHO Collaborating Center for Molecular Biology and Novel Therapeutic Strategies for Rheumatic Diseases, Department of Rheumatology, University of Zürich, Switzerland. ruzsph@ruz.unizh.ch
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
