|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2000-2-24
|
|
pubmed:abstractText |
The delivery of bronchodilator drugs with metered-dose inhaler (MDI) and a spacer in mechanically ventilated patients has become a widespread practice. However, the various ventilator settings that influence the efficacy of MDI are not well established. The tidal volume (VT) during drug delivery has been suggested as one of the factors that might increase the effectiveness of this therapy. To test this, the effect of two different VT on the bronchodilation induced by beta 2-agonists administered with MDI and a spacer in a group of mechanically ventilated patients with chronic obstructive pulmonary disease (COPD) was examined.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0342-4642
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1215-21
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:10654204-Administration, Inhalation,
pubmed-meshheading:10654204-Adrenergic beta-Agonists,
pubmed-meshheading:10654204-Aged,
pubmed-meshheading:10654204-Airway Resistance,
pubmed-meshheading:10654204-Albuterol,
pubmed-meshheading:10654204-Analysis of Variance,
pubmed-meshheading:10654204-Bronchodilator Agents,
pubmed-meshheading:10654204-Cross-Over Studies,
pubmed-meshheading:10654204-Female,
pubmed-meshheading:10654204-Heart Rate,
pubmed-meshheading:10654204-Humans,
pubmed-meshheading:10654204-Lung Diseases, Obstructive,
pubmed-meshheading:10654204-Male,
pubmed-meshheading:10654204-Nebulizers and Vaporizers,
pubmed-meshheading:10654204-Positive-Pressure Respiration,
pubmed-meshheading:10654204-Prospective Studies,
pubmed-meshheading:10654204-Respiratory Mechanics,
pubmed-meshheading:10654204-Tidal Volume
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Bronchodilator delivery by metered-dose inhaler in mechanically ventilated COPD patients: influence of tidal volume.
|
|
pubmed:affiliation |
Intensive Care Unit, University Hospital of Heraklion, University of Crete, Greece.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|
