Source:http://linkedlifedata.com/resource/pubmed/id/10645714
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
48
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pubmed:dateCreated |
2000-2-3
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pubmed:abstractText |
Synovial sarcoma have (about in 95% of the cases) the specific and characteristic reciprocal chromosomal translocation t(X; 18) (p11.2; q 11.2). Application of dual-colour fluorescence in situ hybridization (FISH) on interphase nuclei to identify the specific translocation has a diagnostic importance for daily pathological practice. For visualisation of the translocated chromosomal fragments of synovial sarcoma cells on imprint smears, chromosome X painting probes and chromosome 18 centromeric probes were used. Our present study indicates that the precise preoperative diagnosis of synovial sarcoma using dual-colour FISH is possible on smears and this possibility (to identify specific chromosomal translocations in soft tissue tumours) is a landmark in the preoperative diagnosis of soft tissue sarcomas.
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pubmed:language |
hun
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0030-6002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2691-4
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pubmed:dateRevised |
2009-10-21
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pubmed:meshHeading |
pubmed-meshheading:10645714-Adult,
pubmed-meshheading:10645714-Fingers,
pubmed-meshheading:10645714-Foot,
pubmed-meshheading:10645714-Humans,
pubmed-meshheading:10645714-In Situ Hybridization, Fluorescence,
pubmed-meshheading:10645714-Male,
pubmed-meshheading:10645714-Middle Aged,
pubmed-meshheading:10645714-Sarcoma, Synovial,
pubmed-meshheading:10645714-Soft Tissue Neoplasms,
pubmed-meshheading:10645714-Translocation, Genetic
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pubmed:year |
1999
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pubmed:articleTitle |
[Dual fluorescence in situ hybridization analysis of synovial sarcoma].
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pubmed:affiliation |
Pathologiai Osztály, Haynal Imre Egészségtudományi Egyetem, Onkopathologiai és Citodiagnosztikai Tanszék, Budapest.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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