Source:http://linkedlifedata.com/resource/pubmed/id/10631799
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2000-1-28
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pubmed:abstractText |
A software system, SOSUI, was previously developed for discriminating between soluble and membrane proteins and predicting transmembrane regions (Hirokawa et al., Bioinformatics, 14 (1998) 378-379). The performance of the system was 99% for the discrimination between two types of proteins and 96% for the prediction of transmembrane helices. When all of the amino acid sequences from 15 single-cell organisms were analyzed by SOSUI, the proportion of predicted polytopic membrane proteins showed an almost constant value of 15-20%, irrespective of the total genome size. However, single-cell organisms appeared to be categorized in terms of the preference of the number of transmembrane segments: species with small genomes were characterized by a significant peak at a helix number of approximately six or seven; species with large genomes showed a peak at 10 or 11 helices; and species with intermediate genome sizes showed a monotonous decrease of the population of membrane proteins against the number of transmembrane helices.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0301-4622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-71
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pubmed:dateRevised |
2010-2-23
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pubmed:meshHeading |
pubmed-meshheading:10631799-Archaea,
pubmed-meshheading:10631799-Artificial Intelligence,
pubmed-meshheading:10631799-Bacteria,
pubmed-meshheading:10631799-Membrane Proteins,
pubmed-meshheading:10631799-Open Reading Frames,
pubmed-meshheading:10631799-Proteome,
pubmed-meshheading:10631799-Saccharomyces cerevisiae,
pubmed-meshheading:10631799-Software
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pubmed:year |
1999
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pubmed:articleTitle |
Proportion of membrane proteins in proteomes of 15 single-cell organisms analyzed by the SOSUI prediction system.
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pubmed:affiliation |
Tokyo University of Agriculture and Technology, Department of Biotechnology, Japan.
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pubmed:publicationType |
Journal Article
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