Source:http://linkedlifedata.com/resource/pubmed/id/10622343
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-2-8
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pubmed:abstractText |
Previous research has indicated that laboratory aggression in men increases after temporarily reducing the synthesis and neurotransmission of serotonin (5-HT) in the brain using the plasma L-tryptophan (Trp) depletion technique. Further research indicates that male subjects selected for high trait hostility are particularly prone to increased aggression following plasma Trp depletion. In a recent study of laboratory aggression in male control subjects, we demonstrated that laboratory aggression increased following ingestion of a Trp-depleting beverage, but not after ingestion of a Trp-containing beverage nor under food-restricted conditions. We report here that the increases in aggression under Trp-depleted conditions were specific to men who scored the highest on the Buss-Perry Aggression Questionnaire. These preliminary data support earlier findings that compared to non-hostile men, hostile men may be more prone to behavior change induced by the perturbation of the 5-HT neurotransmitter system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0165-1781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-32
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pubmed:dateRevised |
2008-4-17
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pubmed:meshHeading |
pubmed-meshheading:10622343-Adolescent,
pubmed-meshheading:10622343-Adult,
pubmed-meshheading:10622343-Aggression,
pubmed-meshheading:10622343-Analysis of Variance,
pubmed-meshheading:10622343-Biological Markers,
pubmed-meshheading:10622343-Brain,
pubmed-meshheading:10622343-Hostility,
pubmed-meshheading:10622343-Humans,
pubmed-meshheading:10622343-Male,
pubmed-meshheading:10622343-Psychiatric Status Rating Scales,
pubmed-meshheading:10622343-Self Disclosure,
pubmed-meshheading:10622343-Serotonin,
pubmed-meshheading:10622343-Tryptophan
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pubmed:year |
1999
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pubmed:articleTitle |
Influence of trait hostility on tryptophan depletion-induced laboratory aggression.
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pubmed:affiliation |
Department of Psychiatry and Behavioral Sciences, University of Texas-Houston Medical School, 77030, USA. ddoughrt@msi.uth.tmc.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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