Source:http://linkedlifedata.com/resource/pubmed/id/10607611
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2000-1-7
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pubmed:abstractText |
A restriction enzyme gene is often linked to a modification methylase gene the role of which is to protect a recognition site on DNA from breakage by the former. Loss of some restriction-modification gene complexes leads to cell death through restriction breakage in the genome. Their behavior as genomic parasites/symbionts may explain the distribution of restriction sites and clarify certain aspects of bacterial recombination repair and mutagenesis. A comparison of bacterial genomes supports the hypothesis that restriction-modification gene complexes are mobile elements involved in various genome rearrangements and evolution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0959-437X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
649-56
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10607611-Bacteria,
pubmed-meshheading:10607611-DNA Restriction Enzymes,
pubmed-meshheading:10607611-Evolution, Molecular,
pubmed-meshheading:10607611-Genes, Bacterial,
pubmed-meshheading:10607611-Genome, Bacterial,
pubmed-meshheading:10607611-Host-Parasite Interactions,
pubmed-meshheading:10607611-Interspersed Repetitive Sequences,
pubmed-meshheading:10607611-Mutagenesis,
pubmed-meshheading:10607611-Recombination, Genetic
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pubmed:year |
1999
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pubmed:articleTitle |
Shaping the genome--restriction-modification systems as mobile genetic elements.
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pubmed:affiliation |
Institute of Medical Science, University of Tokyo, Shirokanedai, 108-8639, Japan. ikobaya@ims.u-tokyo.ac.jp
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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