| pubmed-article:10601002 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C0934502 | lld:lifeskim |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C0038446 | lld:lifeskim |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C0549255 | lld:lifeskim |
| pubmed-article:10601002 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:10601002 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:10601002 | pubmed:dateCreated | 2000-1-31 | lld:pubmed |
| pubmed-article:10601002 | pubmed:abstractText | Recordings were made from pairs of neurons in cat striate visual cortex in vitro to study the AMPA-channel-mediated components of intracortical excitatory synaptic connections between layer 4 spiny neurons and between layer 6 and layer 4 spiny neurons. Forty-six of the 72 cells recorded were identified morphologically. They consisted of spiny stellate and pyramidal cells in layer 4, and pyramidal cells in layer 6. Connections between layer 4 excitatory cells involve excitatory postsynaptic potentials (EPSPs) averaging 949 microV, with an average coefficient of variation of 0.21 (n = 30). The synapses operate at very high release probabilities (0.69-0.98). With repetitive stimulation these EPSPs show varying degrees of depression, largely mediated by presynaptic changes in release probability. Four pairs of layer 4 cells were reciprocally connected. The connections from layer 6 to layer 4 involve smaller, more variable EPSPs, with an average amplitude of 214 microV, and average coefficient of variation 0.72 (n = 7). These synapses operate at moderately high release probabilities (0.37-0.56). They show facilitation with repetitive stimulation, mediated largely by presynaptic changes in release probability. One excitatory connection from a layer 4 neuron to a layer 6 pyramidal cell was also detected. Thus, layer 4 spiny neurons receive effective excitation from two intracortical sources that have different synaptic dynamics and are likely to contribute significantly to the temporal properties of these cells in vivo. | lld:pubmed |
| pubmed-article:10601002 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10601002 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10601002 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10601002 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10601002 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10601002 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10601002 | pubmed:issn | 1047-3211 | lld:pubmed |
| pubmed-article:10601002 | pubmed:author | pubmed-author:JackJ JJJ | lld:pubmed |
| pubmed-article:10601002 | pubmed:author | pubmed-author:MartinK AKA | lld:pubmed |
| pubmed-article:10601002 | pubmed:author | pubmed-author:StratfordK... | lld:pubmed |
| pubmed-article:10601002 | pubmed:author | pubmed-author:Tarczy-Hornoc... | lld:pubmed |
| pubmed-article:10601002 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10601002 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10601002 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10601002 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10601002 | pubmed:pagination | 833-43 | lld:pubmed |
| pubmed-article:10601002 | pubmed:dateRevised | 2010-8-25 | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:meshHeading | pubmed-meshheading:10601002... | lld:pubmed |
| pubmed-article:10601002 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10601002 | pubmed:articleTitle | Intracortical excitation of spiny neurons in layer 4 of cat striate cortex in vitro. | lld:pubmed |
| pubmed-article:10601002 | pubmed:affiliation | University Laboratory of Physiology, Oxford, UK. | lld:pubmed |
| pubmed-article:10601002 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10601002 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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