Source:http://linkedlifedata.com/resource/pubmed/id/10594389
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-5-11
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pubmed:abstractText |
Two sensitive and fast spectrophotometric methods using batch and flow-injection procedures for the determination of meloxicam (MX) are proposed. The methods are based on the formation of a green complex between this drug and Fe(III) [2MX/Fe(III)] in a methanolic medium. The calibration graphs resulting from measuring the absorbance at 570 nm are linear over the ranges 2.0-200 and 5.00-250 mg l(-1) with detection limits of 0.47 and 0.72 mg l(-1), respectively. Furthermore, a flow-injection spectrophotometric method involving measurement of the absorbance of the drug at 362 nm in 0.1 M NaOH is presented. The calibration graph is linear over the range 0.5-20 mg l(-1) with a detection limit of 0.04 mg l(-1). The methods are applied to the routine analysis of MX in pharmaceuticals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents...,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Carriers,
http://linkedlifedata.com/resource/pubmed/chemical/Iron,
http://linkedlifedata.com/resource/pubmed/chemical/Tablets,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazines,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/meloxicam
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0928-0987
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
311-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10594389-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:10594389-Calibration,
pubmed-meshheading:10594389-Chemistry, Pharmaceutical,
pubmed-meshheading:10594389-Drug Carriers,
pubmed-meshheading:10594389-Iron,
pubmed-meshheading:10594389-Sensitivity and Specificity,
pubmed-meshheading:10594389-Spectrophotometry,
pubmed-meshheading:10594389-Tablets,
pubmed-meshheading:10594389-Thiazines,
pubmed-meshheading:10594389-Thiazoles
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pubmed:year |
2000
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pubmed:articleTitle |
Spectrophotometric methods for determining meloxicam in pharmaceuticals using batch and flow-injection procedures.
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pubmed:affiliation |
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, 30071-Murcia, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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