Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2000-1-7
pubmed:databankReference
pubmed:abstractText
Multilocus sequence typing and antigen gene sequencing were used to investigate an outbreak of meningococcal disease in a university in the United Kingdom. The data obtained showed that five distinct Neisseria meningitidis strains belonging to the ET-37 complex were present in the student population during the outbreak. Three of these strains were not associated with invasive disease, and two distinct strains caused invasive disease, including several fatalities. The initial case of the disease cluster was caused by a strain distinct from that responsible for at least two subsequent cases and two cases remote from the university, which were epidemiologically linked to the outbreak. These observations were consistent with pulsed-field gel electrophoresis data, but the sequence data alone were sufficient to resolve the strains involved in the disease cluster. Interpretation of the nucleotide sequence data was more straightforward than interpretation of the fingerprint patterns, and the sequence data provided information on the genetic differences among the isolates.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-10225902, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-10368953, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-1350612, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-1500170, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-1904526, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-2412271, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-3108242, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-3125576, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-7592413, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-8057850, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-8114063, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-8501321, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-8581171, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-8837029, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9129587, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9302199, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9501229, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9522450, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9705375, http://linkedlifedata.com/resource/pubmed/commentcorrection/10565901-9747760
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3883-7
pubmed:dateRevised
2011-4-7
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Multilocus sequence typing and antigen gene sequencing in the investigation of a meningococcal disease outbreak.
pubmed:affiliation
Division of Bacteriology, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire EN6 3QG, United Kingdom.
pubmed:publicationType
Journal Article