|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1999-11-24
|
|
pubmed:abstractText |
alpha2-Adrenergic agonists produce analgesia primarily by a spinal action and hypotension and bradycardia by actions at several sites. Clonidine is approved for epidural use in the treatment of neuropathic pain, but its wider application is limited by hemodynamic side effects. This study determined the antinociceptive and hemodynamic effects of a novel alpha2-adrenergic agonist, MPV-2426, in sheep.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0003-3022
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
91
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1425-36
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:10551595-Adrenergic alpha-2 Receptor Agonists,
pubmed-meshheading:10551595-Adrenergic alpha-Agonists,
pubmed-meshheading:10551595-Algorithms,
pubmed-meshheading:10551595-Analgesics,
pubmed-meshheading:10551595-Animals,
pubmed-meshheading:10551595-Blood Gas Analysis,
pubmed-meshheading:10551595-Female,
pubmed-meshheading:10551595-Hemodynamics,
pubmed-meshheading:10551595-Imidazoles,
pubmed-meshheading:10551595-Indans,
pubmed-meshheading:10551595-Injections, Spinal,
pubmed-meshheading:10551595-Regional Blood Flow,
pubmed-meshheading:10551595-Sheep,
pubmed-meshheading:10551595-Spinal Cord
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Antinociceptive and hemodynamic effects of a novel alpha2-adrenergic agonist, MPV-2426, in sheep.
|
|
pubmed:affiliation |
Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. eisenach@wfubmc.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
