To review the preclinical and clinical studies relevant to the prognosis and prognostic associations of BRCA1- and BRCA2-associated breast carcinomas, with an emphasis on research methodology.
Samuel Lunenfeld Research Institute and Marvelle Koffler Breast Center, Mt Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada. PhillipsKelly@petermac.unimelb.edu.au