Source:http://linkedlifedata.com/resource/pubmed/id/10548114
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1999-11-24
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pubmed:abstractText |
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrialized countries. Different risk factors have been associated with AMD. We performed a histopathologic and morphometric study to compare eyes with different stages of AMD to age-matched eyes. This study aimed to investigate the correlation among morphometric characteristics of choroidal vessels, the retinal pigment epithelium, and Bruch's membrane, to study the association between these characteristics and the presence and type of AMD, and to identify morphologic risk factors for exudative AMD. Furthermore, we histologically analyzed surgically removed choroidal neovascular membranes secondary to underlying diseases other than AMD to discern whether the cellular and extracellular components of the membranes of eyes with AMD are similar to those with diseases other than AMD.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0039-6257
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S10-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10548114-Aged,
pubmed-meshheading:10548114-Aged, 80 and over,
pubmed-meshheading:10548114-Aging,
pubmed-meshheading:10548114-Bruch Membrane,
pubmed-meshheading:10548114-Cadaver,
pubmed-meshheading:10548114-Choroid,
pubmed-meshheading:10548114-Choroidal Neovascularization,
pubmed-meshheading:10548114-Humans,
pubmed-meshheading:10548114-Macular Degeneration,
pubmed-meshheading:10548114-Pigment Epithelium of Eye
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pubmed:year |
1999
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pubmed:articleTitle |
Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes.
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pubmed:affiliation |
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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