Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-11-24
pubmed:abstractText
Salmonella typhimurium strains MAE52 and MAE32 display a constitutive multicellular morphotype mediated by the expression of the agfD operon. In those strains, the role of flagella in the formation of various modes of multicellular behavior was investigated. Flagella were not required for the formation of the multicellular morphotype (rdar) on plates. However, visual examination showed that the global behavior of the bacterial community on air-liquid, surface-liquid or cell-cell-liquid interfaces changed in the absence of flagella. No differences in the local cell-cell interactions were observed at the microscopic level. Using Western blot analysis, no co-regulation of flagella and thin aggregative fimbriae, an extracellular component of the multicellular morphotype, was observed either on plates or in standing culture. In a mutant lacking flagella and thin aggregative fimbriae, the contribution of the latter to the multicellular morphotype was dominant. We concluded that independently regulated genes can act in an additive fashion to confer a pronounced multicellular behavior.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0378-1097
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
180
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
91-102
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Flagella modulate the multicellular behavior of Salmonella typhimurium on the community level.
pubmed:affiliation
Division of Cell Biology and Immunology, GBF, Mascheroder Weg 1, D-38124, Braunschweig, Germany. uro@gbf.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't