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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1999-11-30
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pubmed:abstractText |
Ischemia-reperfusion (IR) involves adhesion of leukocytes to the activated endothelium, leading to tissue damage. CD11/CD18 beta(2) integrins interact with their ligands on endothelial cells and may therefore represent a therapeutic target for the prevention of IR. We investigated the effects of three monoclonal antibodies (mAbs) that recognize epitopes of heavy or light chain of the beta(2) integrins on IR in kidneys.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-4804
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pubmed:author |
pubmed-author:Blanc-BrunatNN,
pubmed-author:DubernardJ MJM,
pubmed-author:IshibashiMM,
pubmed-author:KawashimaHH,
pubmed-author:MargonariJJ,
pubmed-author:MartinXX,
pubmed-author:MiyasakaMM,
pubmed-author:PanayiCC,
pubmed-author:RevillardJ PJP,
pubmed-author:SteghensJ PJP,
pubmed-author:TajraL CLC,
pubmed-author:Treille-RitouetDD,
pubmed-author:VivierGG
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pubmed:copyrightInfo |
Copyright 1999 Academic Press.
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pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10527701-Animals,
pubmed-meshheading:10527701-Antibodies, Monoclonal,
pubmed-meshheading:10527701-Antigens, CD18,
pubmed-meshheading:10527701-Ischemia,
pubmed-meshheading:10527701-Kidney,
pubmed-meshheading:10527701-Leukocyte Count,
pubmed-meshheading:10527701-Leukocytes,
pubmed-meshheading:10527701-Lymphocyte Function-Associated Antigen-1,
pubmed-meshheading:10527701-Male,
pubmed-meshheading:10527701-Mice,
pubmed-meshheading:10527701-Rats,
pubmed-meshheading:10527701-Rats, Inbred F344,
pubmed-meshheading:10527701-Reperfusion Injury
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pubmed:year |
1999
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pubmed:articleTitle |
In vivo effects of monoclonal antibodies against rat beta(2) integrins on kidney ischemia-reperfusion injury.
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pubmed:affiliation |
INSERM, Unité 281, Laboratoire de Recherche Chirurgicale, Hôpital Edouard Herriot, Lyon, France.
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pubmed:publicationType |
Journal Article
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