Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-12-7
pubmed:abstractText
Topical nitrates lower anal sphincter pressure and heal anal fissures, but a majority of patients experience headache. The internal anal sphincter has a calcium dependent mechanism to maintain tone, and also receives an inhibitory extrinsic cholinergic innervation. It may therefore be possible to lower anal sphincter pressure using calcium channel blockers and cholinergic agonists without side effects.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-1355544, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-1486447, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-1735328, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-2736353, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-2858571, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-2882174, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-4053894, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-456843, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-7067558, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-773793, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-7953427, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-8017267, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-8242318, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-8620790, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-8696736, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-8988115, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-920890, http://linkedlifedata.com/resource/pubmed/commentcorrection/10517908-9435326
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0017-5749
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
719-22
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects.
pubmed:affiliation
Department of Physiology, St Mark's Hospital, Northwick Park, Watford Road, Harrow, Middlesex HA1 3UJ, UK.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't