Source:http://linkedlifedata.com/resource/pubmed/id/10492384
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-10-22
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pubmed:abstractText |
Behavioral paradigms applicable for use in both human and nonhuman subjects for investigating aspects of timing behavior are presented with a view towards exploring their strengths, weaknesses, and utility in a variety of experimental situations. Tri-peak, peak interval, differential reinforcement of low rate responding, and temporal response differentiation procedures are highlighted. In addition, the application of timing tasks in preclinical and clinical settings is discussed: pharmacological manipulations are providing information on the neurotransmitters involved and species differences; normative data for children are being developed; and noninvasive imaging procedures are being employed in adult human subjects to explore the involvement of specific brain areas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0892-0362
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
491-502
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pubmed:dateRevised |
2009-10-26
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pubmed:meshHeading |
pubmed-meshheading:10492384-Animals,
pubmed-meshheading:10492384-Behavior,
pubmed-meshheading:10492384-Behavior, Animal,
pubmed-meshheading:10492384-Humans,
pubmed-meshheading:10492384-Pharmaceutical Preparations,
pubmed-meshheading:10492384-Reaction Time,
pubmed-meshheading:10492384-Time Perception,
pubmed-meshheading:10492384-Toxicity Tests
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pubmed:articleTitle |
The use of timing behaviors in animals and humans to detect drug and/or toxicant effects.
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pubmed:affiliation |
Behavioral Toxicology Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR 72079-9502, USA. mpaule@nctr.fda.gov
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pubmed:publicationType |
Congresses
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