pubmed-article:10482552 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0037224 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0003316 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C1422036 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0178887 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C1549781 | lld:lifeskim |
pubmed-article:10482552 | lifeskim:mentions | umls-concept:C0449450 | lld:lifeskim |
pubmed-article:10482552 | pubmed:issue | 10 | lld:pubmed |
pubmed-article:10482552 | pubmed:dateCreated | 1999-10-12 | lld:pubmed |
pubmed-article:10482552 | pubmed:abstractText | Cytotoxic T lymphocyte (CTL) responses against the simian immunodeficiency virus (SIV) envelope and Gag proteins were monitored in a Mamu-A*01-positive rhesus macaque infected with SIVsmE660. Peripheral blood mononuclear cells (PBMC) cultured with synthetic peptides spanning the entire gp160 and Gag coding region recognized a total of three epitopes. One located in Gag was identified as the previously described Mamu-A*01-restricted p11cC-->M epitope (CTPYDINQM). The other two epitopes, designated p15m and p54m, were located in the gp160 envelope protein. Both were nine amino acids in length and were predicted to bind Mamu-A*01 because they contained proline and leucine residues at positions 3 and 9, respectively. Indeed, expression of this class I major histocompatibility complex molecule was required for target cell recognition by envelope-specific CD8(+) T cells directed against both epitopes. These Mamu-A*01-restricted epitopes in the SIV envelope will be useful for monitoring immune responses in vaccinated or infected animals. | lld:pubmed |
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pubmed-article:10482552 | pubmed:language | eng | lld:pubmed |
pubmed-article:10482552 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10482552 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:10482552 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10482552 | pubmed:month | Oct | lld:pubmed |
pubmed-article:10482552 | pubmed:issn | 0022-538X | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:JohnsonP RPR | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:AllenTT | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:WalkerC MCM | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:EricksonA LAL | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:WatkinsD IDI | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:SettiEE | lld:pubmed |
pubmed-article:10482552 | pubmed:author | pubmed-author:FurchnerMM | lld:pubmed |
pubmed-article:10482552 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10482552 | pubmed:volume | 73 | lld:pubmed |
pubmed-article:10482552 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10482552 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10482552 | pubmed:pagination | 8035-9 | lld:pubmed |
pubmed-article:10482552 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:10482552 | pubmed:meshHeading | pubmed-meshheading:10482552... | lld:pubmed |
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pubmed-article:10482552 | pubmed:meshHeading | pubmed-meshheading:10482552... | lld:pubmed |
pubmed-article:10482552 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10482552 | pubmed:articleTitle | The simian immunodeficiency virus envelope glycoprotein contains two epitopes presented by the Mamu-A*01 class I molecule. | lld:pubmed |
pubmed-article:10482552 | pubmed:affiliation | Children's Research Institute, Children's Hospital, Inc., Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, USA. | lld:pubmed |
pubmed-article:10482552 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10482552 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:10482552 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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