|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3B
|
|
pubmed:dateCreated |
1999-9-16
|
|
pubmed:abstractText |
In a Phase I study replication-deficient adenovirus containing the herpes simplex virus (HSV) thymidine kinase (TK) gene (AdV-HSV-TK) was instilled intraperitoneally in patients with recurrent ovarian cancer. Patients were treated with Acyclovir (ACV) or Valacyclovir (VCV) as enzymatic substrates. The purpose of this study was to compare serum levels of ACV and VCV.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0250-7005
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2163-5
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10472325-Acyclovir,
pubmed-meshheading:10472325-Administration, Oral,
pubmed-meshheading:10472325-Antiviral Agents,
pubmed-meshheading:10472325-Female,
pubmed-meshheading:10472325-Gene Therapy,
pubmed-meshheading:10472325-Humans,
pubmed-meshheading:10472325-Instillation, Drug,
pubmed-meshheading:10472325-Outpatients,
pubmed-meshheading:10472325-Ovarian Neoplasms,
pubmed-meshheading:10472325-Prodrugs,
pubmed-meshheading:10472325-Simplexvirus,
pubmed-meshheading:10472325-Thymidine Kinase,
pubmed-meshheading:10472325-Valine
|
|
pubmed:articleTitle |
Thymidine kinase (TK) gene therapy of solid tumors: valacyclovir facilitates outpatient treatment.
|
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, Freiburg University Medical Center, Germany.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Clinical Trial, Phase I
|
