rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1999-9-8
|
pubmed:abstractText |
Cardio-vascular diseases are the most common cause of death in industrialized countries. A new marker has emerged among offending risk factors in the past few years: homocysteine. This sulphured amino-acid is an important intermediate in transsulphuration and remethylation reactions of methionine's metabolism. We proposed to evaluate a home made method of determination for this parameter by high performance liquid chromatography (HPLC) and to compare it to fluorescence polarization immunoassay technique (FPIA) and to gaz phase chromatography (CG-SM). This method associated with good sensibility and precision remain much less expensive than FPIA technique.
|
pubmed:language |
fre
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0003-3898
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
474-80
|
pubmed:dateRevised |
2009-11-3
|
pubmed:meshHeading |
pubmed-meshheading:10432372-Acetylcysteine,
pubmed-meshheading:10432372-Biological Markers,
pubmed-meshheading:10432372-Cardiovascular Diseases,
pubmed-meshheading:10432372-Chromatography, High Pressure Liquid,
pubmed-meshheading:10432372-Cysteine,
pubmed-meshheading:10432372-Dipeptides,
pubmed-meshheading:10432372-Fluorescent Antibody Technique,
pubmed-meshheading:10432372-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:10432372-Glutathione,
pubmed-meshheading:10432372-Homocysteine,
pubmed-meshheading:10432372-Humans,
pubmed-meshheading:10432372-Reproducibility of Results,
pubmed-meshheading:10432372-Risk Factors,
pubmed-meshheading:10432372-Sensitivity and Specificity
|
pubmed:articleTitle |
[Blood levels of homocysteine by high pressure liquid chromatography and comparison with two other techniques].
|
pubmed:affiliation |
Laboratoire de biochimie, toxicologie et pharmacologie cliniques, Hôpital d'Instruction des Armées Begin, 69, avenue de Paris, 94163 Saint-Mandé cedex.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|