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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1979-3-24
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pubmed:abstractText |
The susceptibility of 21 strains of Aspergillus (11 of A. fumigatus, 8 of A, niger, and 2 of A. flavus) isolated from human pathologic specimens to Amphotericin B and Miconazole has been comparatively studied. Determination of the minimal inhibitory concentration of both drugs in a liquid medium showed a noticeably variability for the different strains. The values obtained for Amphotericin B varied between 0.25 microgram/ml (2 strains) and 1.25 microgram/ml (5 strains) after 48 hours, and between 1,25 microgram/ml (1 strain) and 50 microgram/ml (1 strain) after 10 days. For Miconazole the results varied between 0.1 microgram/ml (1 strain) and 25 microgram/ml (1 strain) after 48 hours of incubation, and between 0.5 microgram/ml (5 strains) and greater than 100 microgram/ml after 10 days. The variability of these results indicates the usefulness of carrying our in vitro sensitivity studies whenever it is possible.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0301-486X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
64
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:104180-Amphotericin B,
pubmed-meshheading:104180-Aspergillosis,
pubmed-meshheading:104180-Aspergillus,
pubmed-meshheading:104180-Aspergillus flavus,
pubmed-meshheading:104180-Aspergillus fumigatus,
pubmed-meshheading:104180-Aspergillus niger,
pubmed-meshheading:104180-Drug Resistance, Microbial,
pubmed-meshheading:104180-Humans,
pubmed-meshheading:104180-Imidazoles,
pubmed-meshheading:104180-Miconazole,
pubmed-meshheading:104180-Microbial Sensitivity Tests
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pubmed:year |
1978
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pubmed:articleTitle |
Determination of the minimal inhibitory concentration of amphotericin B and miconazole for 21 strains of Aspergillus.
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pubmed:publicationType |
Journal Article,
Comparative Study
|