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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
1999-8-19
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pubmed:abstractText |
Approximately 2.0%-2.5% of Ashkenazi Jewish women carry one of three founding mutations in the BRCA1 and BRCA2 genes, and each mutation is associated with a high lifetime risk of invasive breast cancer. We investigated the extent to which these three mutations contribute to breast cancer incidence in the Ashkenazi Jewish population.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0027-8874
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pubmed:author |
pubmed-author:Allingham-HawkinsDD,
pubmed-author:BlondalJJ,
pubmed-author:BrunetJ SJS,
pubmed-author:ContigaVV,
pubmed-author:Di ProsperoLL,
pubmed-author:FoulkesWW,
pubmed-author:GlendonGG,
pubmed-author:GoodwinPP,
pubmed-author:GossPP,
pubmed-author:HamelNN,
pubmed-author:HoneyfordJJ,
pubmed-author:KleinMM,
pubmed-author:LiedeAA,
pubmed-author:MeschinoWW,
pubmed-author:MoslehiRR,
pubmed-author:NarodSS,
pubmed-author:OzcelikHH,
pubmed-author:PatersonCC,
pubmed-author:SerruyaCC,
pubmed-author:WarnerEE
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1241-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10413426-Aged,
pubmed-meshheading:10413426-Breast Neoplasms,
pubmed-meshheading:10413426-Case-Control Studies,
pubmed-meshheading:10413426-Female,
pubmed-meshheading:10413426-Genes, BRCA1,
pubmed-meshheading:10413426-Genes, Tumor Suppressor,
pubmed-meshheading:10413426-Humans,
pubmed-meshheading:10413426-Jews,
pubmed-meshheading:10413426-Middle Aged,
pubmed-meshheading:10413426-Mutation,
pubmed-meshheading:10413426-Risk,
pubmed-meshheading:10413426-Risk Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer.
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pubmed:affiliation |
Division of Medical Oncology, Toronto-Sunnybrook Regional Cancer Centre, Toronto, ON, Canada. ellen_warner@cancercare.on.ca
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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