Source:http://linkedlifedata.com/resource/pubmed/id/10412682
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-9-9
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pubmed:abstractText |
Local inflammatory reactions at the site of a mosquito bite are frequent. Immediate systemic reactions have occasionally been reported. The first case of a patient with relapsing episodes of a serum sickness-like syndrome following mosquito bites is reported herein. A 62-year-old patient came to the emergency room complaining of sudden malaise, chills, fever, headache, cervical lymph node enlargement, arthromyalgia, generalized purpura and leukopenia 6 h after a mosquito bite. He had experienced multiple similar episodes in the last 20 years, also following mosquito bites. Infectious and autoimmune diseases were ruled out. Serum IgE was 9,102 kU/l. Prick test of whole-body Culex pipiens extract was positive. Specific IgE to Aedes communis was 2.25 kU/l. SDS-PAGE immunoblotting of the patient's serum with whole-body C. pipiens extract revealed 43 and 17 kDa IgG-binding proteins and 22 and 17 kDa IgE-binding proteins, neither of which were found with control sera. Skin biopsy was consistent with leukocytoclastic vasculitis. The presence of both mosquito-specific IgE and IgG in the patient's serum suggest a possible cooperative immune response leading to clinical manifestations of serum sickness.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1018-9068
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
190-2
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10412682-Animals,
pubmed-meshheading:10412682-Antigens,
pubmed-meshheading:10412682-Culicidae,
pubmed-meshheading:10412682-Humans,
pubmed-meshheading:10412682-Immunoblotting,
pubmed-meshheading:10412682-Immunoglobulin E,
pubmed-meshheading:10412682-Immunoglobulin G,
pubmed-meshheading:10412682-Insect Bites and Stings,
pubmed-meshheading:10412682-Male,
pubmed-meshheading:10412682-Middle Aged,
pubmed-meshheading:10412682-Serum Sickness,
pubmed-meshheading:10412682-Skin Tests,
pubmed-meshheading:10412682-Vasculitis, Leukocytoclastic, Cutaneous
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pubmed:articleTitle |
Serum sickness-like syndrome due to mosquito bite.
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pubmed:affiliation |
Department of Medicine, Hospital Universitari Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
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pubmed:publicationType |
Journal Article,
Case Reports
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