Linked Life Data

10399701

Source:http://linkedlifedata.com/resource/pubmed/id/10399701

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-7-22
pubmed:abstractText
It was in 1909 that Carlos Chagas described the disease which now bears his name. During the ensuing 90 years, our knowledge of this apparently whimsical, protozoan disease has grown enormously but many points remain unclear. Epidemiologically speaking, current knowledge is poor about the mechanisms and markers of variability of Trypanosoma cruzi, mechanisms allowing the organism to survive in the host, and susceptibility of infected individuals to disabling or fatal late complications. With regard to vector control, it is increasingly obvious that success will be more difficult than previously thought due to the likelihood that, as domestic species are exterminated, they will be replaced by semi-domesticated or wild species. Two other factors that have significantly changed the conventional epidemiological profile of Chagas'disease on the subcontinent over the past 50 years are human intervention in the environment and population migration from rural to urban zones. Despite the breakthroughs achieved in the last decade. Chagas'disease, with its multiple modes of transmission (vector-borne, congenital, and transfusional to name but the most important), diverse reservoir involving over 175 species, and potential for course of the disease in man, will remain a major health problem in Latin America countries for many years to come.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0025-682X
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
391-402
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[American human trypanosomiasis 90 years after its discovery by Carlos Chagas. I. Epidemiology and control].
pubmed:affiliation
Laboratoire de Pathologie Parasitaire et Exotique, Faculté de Médecine Necker-Enfants Malades, Université Paris V René Descartes, France. pays@necker.fr
pubmed:publicationType
Journal Article, English Abstract, Review