Source:http://linkedlifedata.com/resource/pubmed/id/10388472
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1999-7-16
|
pubmed:abstractText |
Although germline mutations in BRCA1 play a central role in familial breast and ovarian cancers, to date, no somatic mutations in BRCA1 have been reported in sporadic breast cancer, and only five somatic mutations have been identified in the sporadic ovarian carcinomas. Because loss of heterozygosity appears frequently at the BRCA1 locus in nonfamilial breast and ovarian carcinomas, we searched for mutations in the BRCA1 gene in sporadic ovarian tumors.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0009-9147
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
45
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
976-81
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10388472-Alleles,
pubmed-meshheading:10388472-BRCA1 Protein,
pubmed-meshheading:10388472-DNA, Neoplasm,
pubmed-meshheading:10388472-Female,
pubmed-meshheading:10388472-Humans,
pubmed-meshheading:10388472-Mutation,
pubmed-meshheading:10388472-Nucleic Acid Hybridization,
pubmed-meshheading:10388472-Ovarian Neoplasms,
pubmed-meshheading:10388472-Polymerase Chain Reaction
|
pubmed:year |
1999
|
pubmed:articleTitle |
BRCA1 gene mutations in sporadic ovarian carcinomas: detection by PCR and reverse allele-specific oligonucleotide hybridization.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, Division of Gynecology, General Hospital of Vienna, University of Vienna, A-1090 Vienna, Austria.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|