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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-7-12
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pubmed:databankReference |
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pubmed:abstractText |
Surfactant proteins A and D are collectins which are considered to play an important role in the innate immunity of lungs. Our aim was to investigate whether surfactant protein A or D is expressed in the porcine Eustachian tube originating from the upper airways. Both surfactant proteins A and D were present in the epithelial cells of the Eustachian tube, as shown by strong immunostaining. Using RT-PCR and Northern hybridization, these collectins were detected in the Eustachian tube. The present study is the first report demonstrating surfactant protein gene expression in the Eustachian tube. Surfactant proteins A and D may be important in the antibody-independent protection of the middle ear.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
452
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10386578-Animals,
pubmed-meshheading:10386578-Base Sequence,
pubmed-meshheading:10386578-Blotting, Northern,
pubmed-meshheading:10386578-Cattle,
pubmed-meshheading:10386578-Epithelial Cells,
pubmed-meshheading:10386578-Eustachian Tube,
pubmed-meshheading:10386578-Glycoproteins,
pubmed-meshheading:10386578-Humans,
pubmed-meshheading:10386578-Immunohistochemistry,
pubmed-meshheading:10386578-Mice,
pubmed-meshheading:10386578-Molecular Sequence Data,
pubmed-meshheading:10386578-Proteolipids,
pubmed-meshheading:10386578-Pulmonary Surfactant-Associated Protein D,
pubmed-meshheading:10386578-Pulmonary Surfactant-Associated Proteins,
pubmed-meshheading:10386578-Pulmonary Surfactants,
pubmed-meshheading:10386578-RNA, Messenger,
pubmed-meshheading:10386578-Rats,
pubmed-meshheading:10386578-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10386578-Sequence Alignment,
pubmed-meshheading:10386578-Sequence Homology, Nucleic Acid,
pubmed-meshheading:10386578-Sheep,
pubmed-meshheading:10386578-Swine
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pubmed:year |
1999
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pubmed:articleTitle |
Surfactant protein A and D expression in the porcine Eustachian tube.
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pubmed:affiliation |
Biocenter Oulu and Department of Pediatrics, University of Oulu, Finland. rpaanane@sun3.oulu.fi
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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