Source:http://linkedlifedata.com/resource/pubmed/id/10377358
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
13
|
| pubmed:dateCreated |
1999-7-15
|
| pubmed:abstractText |
We examined neural activity in prefrontal (PF) cortex of monkeys performing a delayed paired associate task. Monkeys were cued with a sample object. Then, after a delay, a test object was presented. If the test object was the object associated with the sample during training (i.e., its target), they had to release a lever. Monkeys could bridge the delay by remembering the sample (a sensory-related code) and/or thinking ahead to the expected target (a prospective code). Examination of the monkeys' behavior suggested that they were relying on a prospective code. During and shortly after sample presentation, neural activity in the lateral PF cortex primarily reflected the sample. Toward the end of the delay, however, PF activity began to reflect the anticipated target, which indicated a prospective code. These results provide further confirmation that PF cortex does not simply buffer incoming visual inputs, but instead selectively processes information relevant to current behavioral demands, even when this information must be recalled from long-term memory.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
|
| pubmed:issn |
0270-6474
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
19
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
5493-505
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:10377358-Action Potentials,
pubmed-meshheading:10377358-Animals,
pubmed-meshheading:10377358-Behavior, Animal,
pubmed-meshheading:10377358-Cell Count,
pubmed-meshheading:10377358-Conditioning (Psychology),
pubmed-meshheading:10377358-Cues,
pubmed-meshheading:10377358-Female,
pubmed-meshheading:10377358-Macaca mulatta,
pubmed-meshheading:10377358-Male,
pubmed-meshheading:10377358-Memory, Short-Term,
pubmed-meshheading:10377358-Mental Processes,
pubmed-meshheading:10377358-Mental Recall,
pubmed-meshheading:10377358-Neurons,
pubmed-meshheading:10377358-Photic Stimulation,
pubmed-meshheading:10377358-Prefrontal Cortex,
pubmed-meshheading:10377358-Psychomotor Performance,
pubmed-meshheading:10377358-Reaction Time,
pubmed-meshheading:10377358-Time Factors,
pubmed-meshheading:10377358-Visual Perception
|
| pubmed:year |
1999
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| pubmed:articleTitle |
Prospective coding for objects in primate prefrontal cortex.
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| pubmed:affiliation |
Department of Brain and Cognitive Sciences, Center for Learning and Memory, and RIKEN-MIT Neuroscience Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|