Source:http://linkedlifedata.com/resource/pubmed/id/10360872
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1999-6-17
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pubmed:abstractText |
Chlorocresols are used as preservatives in numerous commercial drugs that have been shown to induce myoplasmic Ca2+ release; the most potent isoform is 4-chloro-m-cresol. The aims of this study were to (1) examine the in vivo effects of 4-chloro-m-cresol on swine susceptible to malignant hyperthermia and (2) contrast in vivo versus in vitro dose-response curves.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0003-3022
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1723-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10360872-Animals,
pubmed-meshheading:10360872-Cresols,
pubmed-meshheading:10360872-Hemolysis,
pubmed-meshheading:10360872-Malignant Hyperthermia,
pubmed-meshheading:10360872-Muscle Contraction,
pubmed-meshheading:10360872-Preservatives, Pharmaceutical,
pubmed-meshheading:10360872-Swine
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pubmed:year |
1999
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pubmed:articleTitle |
4-chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations.
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pubmed:affiliation |
Department of Anesthesiology, University of Minnesota, Minneapolis 55455, USA. iaizz001@tc.umn.edu
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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