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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
10
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pubmed:dateCreated |
1999-7-22
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pubmed:abstractText |
The identification, synthesis and activity of a novel class of piperidine renin inhibitors is presented. The most active compounds show activities in the picomolar range and are among the most potent renin inhibitors ever identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:BinggeliAA,
pubmed-author:BreyRR,
pubmed-author:BumAA,
pubmed-author:FischliWW,
pubmed-author:GüllerRR,
pubmed-author:HirthGG,
pubmed-author:MärkiH PHP,
pubmed-author:MüllerMM,
pubmed-author:OefnerCC,
pubmed-author:ScaloneMM,
pubmed-author:StadlerHH,
pubmed-author:VieiraEE,
pubmed-author:WilhelmMM,
pubmed-author:WostlWW
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|
pubmed:issnType |
Print
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|
pubmed:day |
17
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|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1397-402
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
|
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pubmed:year |
1999
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|
pubmed:articleTitle |
Substituted piperidines--highly potent renin inhibitors due to induced fit adaptation of the active site.
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pubmed:affiliation |
Pharma Research Department, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
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pubmed:publicationType |
Journal Article
|
