Source:http://linkedlifedata.com/resource/pubmed/id/10348241
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1999-6-8
|
| pubmed:abstractText |
A large-scale longitudinal cohort project was initiated in western Kenya in June 1992. Between June 1992 and July 1994, 1,848 children less than 15 years of age were monitored prospectively for a mean of 236 days. During this period, 12,035 blood smears were examined for malaria and only 34% were found to be negative. Parasite prevalence (all species) decreased with age (from a high of 83% among children 1-4 years old to 60% among children 10-14 years old). Even more dramatic decreases were noted in the prevalence of high density falciparum infection (from 37% among children 12-23 months old to < 1% among 10-14-year-old children) and in clinical malaria (20% to 0.3% in the same age groups). Children < 1 year of age accounted for 55% of all cases of anemia detected. Anemia was consistently associated with high density infection in children < 10 years of age (20% to 210% increased risk relative to aparasitemic children). These results demonstrate the relationship between high-density malaria infection and two clinical manifestations of malarial illness.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0002-9637
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
641-8
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:10348241-Adolescent,
pubmed-meshheading:10348241-Age Distribution,
pubmed-meshheading:10348241-Anemia,
pubmed-meshheading:10348241-Animals,
pubmed-meshheading:10348241-Child,
pubmed-meshheading:10348241-Child, Preschool,
pubmed-meshheading:10348241-Cohort Studies,
pubmed-meshheading:10348241-Female,
pubmed-meshheading:10348241-Humans,
pubmed-meshheading:10348241-Infant,
pubmed-meshheading:10348241-Infant, Newborn,
pubmed-meshheading:10348241-Kenya,
pubmed-meshheading:10348241-Longitudinal Studies,
pubmed-meshheading:10348241-Malaria, Falciparum,
pubmed-meshheading:10348241-Male,
pubmed-meshheading:10348241-Parasitemia,
pubmed-meshheading:10348241-Plasmodium falciparum,
pubmed-meshheading:10348241-Prevalence,
pubmed-meshheading:10348241-Seasons
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Longitudinal cohort study of the epidemiology of malaria infections in an area of intense malaria transmission II. Descriptive epidemiology of malaria infection and disease among children.
|
| pubmed:affiliation |
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|