Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-7-21
pubmed:abstractText
Concern over human breast milk contamination with the pesticide DDT (1,1,1-trichloro-2,2-bis(chlorodiphenyl)ethane) has prompted numerous studies around the world during the last five decades. This article examines trends in reported DDT levels, and the apparent effect of restrictions on DDT use.
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0300-5771
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-88
pubmed:dateRevised
2004-11-17
pubmed:otherAbstract
PIP: DDT, a pesticide, was first used in the 1940s to control wartime typhus and agricultural pests. However, its harmful effects upon wildlife led to the imposition of a ban upon its routine use in the US and many other countries in the 1970s. Concerns now exist over DDT's persistence in the environment, its bioaccumulation, and its potential for causing cancer and reproductive problems. Despite the availability of alternatives, DDT continues to be used, largely to control malaria-carrying mosquitoes. Human breast milk can be used to monitor levels of lipophilic organochlorine compounds such as DDT. Global trends are examined in reported DDT levels, as well as the apparent effect of restrictions upon DDT use. More than 130 published values for DDT in human milk since 1951 were compiled, and trend lines fit for regions of the world. Population means of DDT in breast milk declined throughout much of the world, from 5000-10,000 mcg DDT/kg milk fat to around 1000 today in many areas. Although different regions have different means, the decline observed in some countries nonetheless corresponds to their restriction of DDT use. Levels can still be high in areas still using DDT, even higher than the World Health Organization's recommended ceiling for infants. These results demonstrate that population averages can be reduced by a predictable amount when DDT use is restricted.
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Worldwide trends in DDT levels in human breast milk.
pubmed:affiliation
Environmental Health Investigations Branch, California Department of Health Services, Oakland 94612-1404, USA.
pubmed:publicationType
Journal Article