|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0023688,
umls-concept:C0205314,
umls-concept:C0220781,
umls-concept:C0242402,
umls-concept:C0243071,
umls-concept:C0257309,
umls-concept:C0439097,
umls-concept:C0679622,
umls-concept:C1547348,
umls-concept:C1705241,
umls-concept:C1883254
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1999-8-19
|
|
pubmed:abstractText |
Two focused libraries of delta opioid ligands were synthesised using AlCl3 facilitated aminolysis. Several compounds were identified with DOR binding affinities higher or similar to SNC-80. A novel acyclic derivative of SNC-80 produced antinociception in the acetic acid abdominal constriction test, which is at least partially mediated via the delta-opioid receptor.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
3
|
|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1329-34
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis.
|
|
pubmed:affiliation |
Organon Laboratories Ltd., Newhouse, Scotland, UK.
|
|
pubmed:publicationType |
Journal Article
|
