Source:http://linkedlifedata.com/resource/pubmed/id/10335499
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1999-8-3
|
pubmed:abstractText |
Gene therapy in Parkinson's disease (PD) emerged about 10 years ago but until now, no clinical trials are under way, because most approaches have failed to show long-term therapeutic effects in PD animal models and because safety concerns precluded the use in humans so far. This review tries to give an overview on the development of different strategies in gene therapy in PD animal models and point out new and possibly more successful directions, including the transplantation of neural precursor cells and pig tissue.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0303-6995
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
55
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
131-47
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10335499-Animals,
pubmed-meshheading:10335499-Cell Line,
pubmed-meshheading:10335499-Disease Models, Animal,
pubmed-meshheading:10335499-Dopamine,
pubmed-meshheading:10335499-Gene Therapy,
pubmed-meshheading:10335499-Neuroprotective Agents,
pubmed-meshheading:10335499-Parkinson Disease, Secondary,
pubmed-meshheading:10335499-Rats,
pubmed-meshheading:10335499-Stem Cells,
pubmed-meshheading:10335499-Transplantation, Heterologous
|
pubmed:year |
1999
|
pubmed:articleTitle |
Somatic gene therapy in animal models of Parkinson's disease.
|
pubmed:affiliation |
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Federal Republic of Germany.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|